A dynamical model of oocyte maturation unveils precisely orchestrated meiotic decisions.
Maturation of vertebrate oocytes into haploid gametes relies on two consecutive meioses without intervening DNA replication.The temporal sequence of cellular transitions driving eggs from G2 arrest to meiosis I (MI) and then to meiosis II (MII) is controlled by the interplay read more between cyclin-dependent and mitogen-activated protein kinases.I